Iodopropynyl Butylcarbamate

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87% Breast implants
86% Tummy tuck
85% Pixel laser
83% Invisalign
82% Blepharoplasty
82% Silicone breast implants
81% Smart Lipo
80% Saline breast implants
79% Facelift
79% VASER Liposelection
76% Laser hair removal
75% Laser resurfacing
75% Lasik
74% Botox
73% Permanent makeup
71% Rhinoplasty
70% Deep FX
70% Fraxel Repair
68% Active FX
66% Chemical peel
64% Juvederm
63% Microdermabrasion
61% Restylane
61% Perlane
58% Sculptra
56% Liposuction
54% IPL
53% Radiesse
52% Fraxel Laser
50% Accent XL
49% Mesotherapy
42% Zoom teeth whitening
41% Lifestyle lift
40% TITAN
37% Lipodissolve
37% Thermage
33% Brite Smile
18% Velasmooth
18% Velashape
14% Thread lift

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Iodopropynyl Butylcarbamate, also known as IPBC, is a white or slightly off-white crystalline powder that contains iodine. It is used in a wide variety of cosmetics and personal-care products

The safety of Iodopropynyl Butylcarbamate has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that Iodopropynyl Butylcarbamate was safe as a cosmetic ingredient at concentrations less than or equal to 0.1%. Iodopropynyl Butylcarbamate should not be used in products intended to be aerosolized.CIR Safety Review: The CIR Expert Panel noted the low degree of sensitization observed in some studies and acknowledged the mild dermal irritation potential of Iodopropynyl Butylcarbamate at concentrations of 0.5% and above. Iodopropynyl Butylcarbamate was negative in tests for mutagenicity, carcinogenicity and reprodutive and developmental toxicity.

The CIR Expert Panel expressed concern about inhalation toxicity with Iodopropynyl Butylcarbamate and thereby concluded that it should not be included in cosmetics and personal-care products meant to be aerosolized. Because the highest concentration tested for comedogenicity was 0.1%, the CIR Expert Panel considered that concentration to be the highest for which the available data would support safety.

The use of Iodopropynyl Butylcarbamate in cosmetics in the European Union is subject to the restrictions described in Annex VI, Part I of the Cosmetics Directive. This preservative may be used in cosmetics and personal care products at a maximum concentration of 0.02% in rinse-off products, and at 0.01% in leave-on products, except in deodorant/antiperspirant products in which the limit is 0.0075%. Iodopropynyl Butylcarbamate is not to be used for oral hygiene and lip-care products, or in products intended to be used on a large part of the body, such as body lotion. With the exception of bath products and shampoo Iodopropynyl Butylcarbamate should not be used in products intended for children under 3 years of age.
Link to the EU Cosmetics Directive: http://ec.europa.eu/enterprise/cosmetics/html/consolidated_d...

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