Triacetin

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Percent of consumer reviews saying "Yes":

87% Breast implants
86% Tummy tuck
85% Pixel laser
83% Invisalign
82% Blepharoplasty
82% Silicone breast implants
81% Smart Lipo
80% Saline breast implants
79% VASER Liposelection
79% Facelift
76% Laser hair removal
75% Laser resurfacing
75% Lasik
74% Botox
73% Permanent makeup
71% Rhinoplasty
70% Fraxel Repair
70% Deep FX
68% Active FX
66% Chemical peel
64% Juvederm
63% Microdermabrasion
61% Restylane
61% Perlane
58% Sculptra
56% Liposuction
54% IPL
53% Radiesse
52% Fraxel Laser
50% Accent XL
49% Mesotherapy
42% Zoom teeth whitening
41% Lifestyle lift
40% TITAN
37% Lipodissolve
37% Thermage
33% Brite Smile
18% Velasmooth
18% Velashape
14% Thread lift

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Triacetin, an oil, is the triester of Glycerol and Acetic Acid. In cosmetics and personal-care products, it is used in makeup as well as in nail polish and nail enamel removers.

The Food and Drug Administration (FDA) has reviewed the safety of Triacetin and determined that it was Generally Recognized As Safe (GRAS) for use as a direct food substance.

The safety of Triacetin has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel reviewed the scientific data and concluded that Triacetin was safe as used in cosmetic formulations.CIR Safety Review: The CIR Expert Panel considered the FDA’s affirmation of glycerides, including Triacetin, as a GRAS human food ingredient as support of the overall safety of this ingredient for cosmetic use. The CIR Expert Panel concluded that the use of Triacetin in cosmetics does not present a risk of reproductive or developmental toxicity because Triacetin is hydrolyzed to glycerol and acetic acid, and these chemicals are not developmental toxins.

The CIR Expert Panel also noted reports indicating that 1,2-Glyceryl diesters can affect cell growth and proliferation. Although Triacetin is a Glyceryl triester, there would be some small amounts of Glyceryl diesters present, some of which could be 1,2-Glyceryl diesters. The CIR Expert Panel concluded, however, that the effects of 1,2-Glyceryl diesters require ester chains longer than two carbon atoms on the Glycerin backbone. Thus, any Glyceryl 1,2-Diacetyl esters present in Triacetin would be not increase cell growth.

FDA: Link to the Code of Federal Regulations for Triacetin
http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRS...

Triacetin may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Directive of the European Union. Ingredients of animal origin must comply with European Union animal by-products regulations.
Link to the EU Cosmetics Directive
http://ec.europa.eu/enterprise/cosmetics/html/consolidated_d...

The Joint FAO/WHO Expert Committee on Food Additives has not specified an Acceptable Daily Intake (ADI) for Triacetin. Total daily intake of Triacetin does not, in the opinion of the Committee, represent a hazard to health, and the establishment of an ADI in mg/kg bw is not deemed necessary. http://www.inchem.org/documents/jecfa/jecmono/v08je12.htm

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