Fast facts

Perlane


What it is: Perlane is an injectable dermal filler composed of hyaluronic acid.  Perlane is used by doctors to restore facial volume and correct various signs of aging.  Perlane is similar to Restylane, but  it has a slightly different chemical composition with larger gel particles for the purpose of deeper injection and correction.


What it addresses:  Moderate to severe facial conditions including:

- Facial wrinkles
- Sunken cheeks
- Nasolabial folds
- Cheek augmentation


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Question

Can the use of Hyaluronic acid to dissolve a lump from Perlane cause a complication?

I had Perlane injected on marionette lines and it seems that they were overfilled or not done properly since I have a lump the about the size of my thumb next to my mouth. This was done about one month ago, and when I asked the doctor to try dissolving the lump using Hyaluronic acid, he said he had never used it before and would rather just put in more Perlane. Is there a problem with using Hyaluronic Acid? Would I be just making a problem worse?


Asked by: gail3
Dothan, Al

Answers (2)

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1
October 22, 2008

Hyaluronidase often can correct errors

Mary Lupo, MD
Mary Lupo, MD
Board Certified
Dermatologist
Answer by Mary Lupo, MD

The procedure you are thinking about is injection with the enzyme called hyaluronidase which can dissolve unwanted or incorrectly placed hyaluronic acid fillers such as Perlane, Restylane, Juvederm, and Prevelle. I have never heard of problems with this injection. In compounded products, there is a risk of allergy, so a skin test can be performed first, but with the FDA approved products, allergies have not been reported. In general, all hyaluronic acid fillers are effective and safe and have high patient satisfaction when injected by an experience dermatologist or plastic surgeon into appropriate candidates.

2
October 22, 2008

Wydase Hyaluronidase Can Be Used To Reduce Restylane Perlane Juvederm or Elevess

I am sorry to learn of the difficulty that you are experiencing. Perlane, Juvederm, Restylane or Elevess are all Hyaluronic Acids (HA).   The beauty of them is that  they are soft and work well to fill in lines and wrinkles around the face.  Side effects from these fillers and dissatisfaction is rare.  When  these occasions do occur the wonderful thing about this group  of fillers is that we can offer Wydase or Hyaluronidase to reduce or dissolve them.  As an Ocular Plastic surgeon, in the suburbs of Detroit, I utlize Wydase all of the time as part of my freezing solution for eyelid surgery.  Side effects from this substance are rare with the most common being an allergic reaction ( which I personally have never encountered with over 3000 procedures, Knock wood:))  As I cannot see you it is impossible to state if masking the lump with more filler would answer the problem.  Your physician should never perform any procedure he/ she is not comfortable with.  I would ask you to return to your trusted physician to see if he could consult a colleague who would be happy to work with both of you.

Comments (1)
sharon ferguson
sharon ferguson
11/15/08

When you are unhappy with a treatment always go back to your Doctor to give them a chance to correct to your satisfaction. They should schedule a 1 wk follow up anyway.

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