Smoking has toxins as well as nicotine which is a vasoconstrictor (decreases size of lumen of blood vessels) which in turn drastically reduces the blood supply to the surgical site and bone graft. As well, a smaller blood vessel cannot move toxins and waste as quickly away from the surgical site. All told, not having enough nutrients and oxygen reaching the bone graft and not being able to rid the site of toxins will have a deleterious effect on the graft. The scientific literature is replete with examples and studies demonstrating that smokers have a significantly higher chance of failure over non-smokers. Having said that, there are many patient who smoke who proceed with surgeries of various kind and are successful. It's jus that your RISK of complications is significantly higher, depending on the type of procedure.